Flash Chromatography
![]() | BUCHI offers the best solution for flash chromatography with extended pressure range |
Natural Compounds
Natural compounds are more and more evaluated as alternatives to classical drugs and therefore the needs for the separation of such complex mixtures are also growing. Flash chromatography is a very valuable technique in the field of natural compounds research because it provides a fast and economical way to separate the main components of complex plant extracts.
Such an application is a perfect illustration of the main advantages of the BUCHI Sepacore system:
- High pressure capability for reversed phase separations even on MPLC columns
- Easy visual monitoring of the separation with glass columns
- Precise and reproducible gradient for complex separations
BUCHI Sepacore Flash Chromatography system for the separation of plant extracts
Synthesis raw mixtures
Flash chromatography is the most often used purification tool after organic synthesis. The following "Short Notes" illustrate the flexibility of the Sepacore system for the optimisation of the flash purification of various synthesis reaction mixtures.
Isolation of 4-Methoxyacetophenone from a crude reaction mixture
Isolation of Benzoin from a crude reaction mixture
Isolation of 2,2'- Furoin from a crude reaction mixture
Cleaning up of α- Methylstyrene by flash chromatography
Isolation of 3-Nitro-ethoxybenzaldehyde from a synthesis mixture
Isolation of Benzylideneacetophenone from a crude reaction mixture



